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Colorectal cancer: CCR by NGS

Speciality(ies) / Other Speciality(ies)

Oncology

Gastroenterology, Pathology

Methodology

NGS

SNS Code

34900

OMIM

Gene Number

Test / Mutation List

Mutations (Hotspots): BRAF; EGFR; ERBB2 (HER2); ERBB3 (HER3); KRAS; NRAS; PIK3CA
Fusion drivers: NTRK1; NTRK2; NTRK3
CNVs: HER2; MET
(To allow a correct CNV analysis the percentage of neoplastic cells in the sample should be higher than a 50%)

TAT

10 to 15 working days

Sample Type

Formalin fix and paraffin embed tumour tissue; stable at room temperature (RT)
(6×20μm sections or tissue block or cellblock, with a fresh H&E slide)
or
Cytological sample in collection medium; stable for 4-6 weeks