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Lung cancer: Lung Extended by NGS

Speciality(ies) / Other Speciality(ies)

Oncology

Pulmonary Oncology, Pathology

Methodology

NGS

SNS Code

34900

OMIM

Gene Number

Test / Mutation List

Mutations (Hotspots): AKT1; ALK; BRAF; DDR2; EGFR; FGFR2; FGFR3; HER2; HER3; HER4; KRAS; MAP2K1; MET; NRAS; PIK3CA; RET; ROS1
Fusion drivers: ALK; FGFR1; FGFR2; FGFR3; MET (exon 14 skipping); NTRK1; NTRK2; NTRK3; ROS1; RET
CNVs: EGFR; FGFR1; HER2; KRAS; MET
(To proceed with CNVs analysis it is necessary the percentage of neoplastic cells in the sample)

TAT

10 to 15 working days

Sample Type

Formalin fix and paraffin embed tumour tissue; stable at room temperature (RT)
(6×20μm sections or tissue block or cellblock, with a fresh H&E slide)
or
Cytological sample in collection medium; stable for 4-6 weeks